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Stabilization, Characterization, and Selective Removal of Cystatin C Amyloid Oligomers

The pathophysiological process in amyloid disorders usually involves the transformation of a functional monomeric protein via potentially toxic oligomers into amyloid fibrils. The structure and properties of the intermediary oligomers have been difficult to study due to their instability and dynamic...

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Hlavní autoři: Östner, Gustav, Lindström, Veronica, Hjort Christensen, Per, Kozak, Maciej, Abrahamson, Magnus, Grubb, Anders
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675580/
https://ncbi.nlm.nih.gov/pubmed/23629649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469593
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