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Single base-pair mutations in centromere element III cause aberrant chromosome segregation in Saccharomyces cerevisiae.

In this paper we show that a 211-base pair segment of CEN3 DNA is sufficient to confer wild-type centromere function in the yeast Saccharomyces cerevisiae. We used site-directed mutagenesis of the 211-base pair fragment to examine the sequence-specific functional requirements of a conserved 11-base...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McGrew, J, Diehl, B, Fitzgerald-Hayes, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC367543/
https://ncbi.nlm.nih.gov/pubmed/3537689
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