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Fusion genes and their discovery using high throughput sequencing
Fusion genes are hybrid genes that combine parts of two or more original genes. They can form as a result of chromosomal rearrangements or abnormal transcription, and have been shown to act as drivers of malignant transformation and progression in many human cancers. The biological significance of f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3675181/ https://ncbi.nlm.nih.gov/pubmed/23376639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.01.011 |
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