FcRγ Controls the Fas-Dependent Regulatory Function of Lymphoproliferative Double Negative T Cells

Patients with autoimmune lymphoproliferative syndrome (ALPS) and lymphoproliferation (LPR) mice are deficient in Fas, and accumulate large numbers of αβ-TCR(+), CD4(−), CD8(−) double negative (DN) T cells. The function of these DN T cells remains largely unknown. The common γ subunit of the activati...

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Autori principali: Juvet, Stephen C., Thomson, Christopher W., Kim, Edward Y., Han, Mei, Zhang, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675138/
https://ncbi.nlm.nih.gov/pubmed/23762329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065253
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