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Signal Peptide Cleavage from GP5 of PRRSV: A Minor Fraction of Molecules Retains the Decoy Epitope, a Presumed Molecular Cause for Viral Persistence

Porcine reproductive and respiratory syndrome virus (PRRSV) is the major pathogen in the pig industry. Variability of the antigens and persistence are the biggest challenges for successful control and elimination of the disease. GP5, the major glycoprotein of PRRSV, is considered an important target...

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Main Authors: Thaa, Bastian, Sinhadri, Balaji Chandrasekhar, Tielesch, Claudia, Krause, Eberhard, Veit, Michael
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675037/
https://ncbi.nlm.nih.gov/pubmed/23755249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065548
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