Histone Acetyl Transferase 1 Is Essential for Mammalian Development, Genome Stability, and the Processing of Newly Synthesized Histones H3 and H4

Histone acetyltransferase 1 is an evolutionarily conserved type B histone acetyltransferase that is thought to be responsible for the diacetylation of newly synthesized histone H4 on lysines 5 and 12 during chromatin assembly. To understand the function of this enzyme in a complex organism, we have...

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Main Authors: Nagarajan, Prabakaran, Ge, Zhongqi, Sirbu, Bianca, Doughty, Cheryl, Agudelo Garcia, Paula A., Schlederer, Michaela, Annunziato, Anthony T., Cortez, David, Kenner, Lukas, Parthun, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675013/
https://ncbi.nlm.nih.gov/pubmed/23754951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003518
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