RSR-2, the Caenorhabditis elegans Ortholog of Human Spliceosomal Component SRm300/SRRM2, Regulates Development by Influencing the Transcriptional Machinery

Protein components of the spliceosome are highly conserved in eukaryotes and can influence several steps of the gene expression process. RSR-2, the Caenorhabditis elegans ortholog of the human spliceosomal protein SRm300/SRRM2, is essential for viability, in contrast to the yeast ortholog Cwc21p. We...

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Main Authors: Fontrodona, Laura, Porta-de-la-Riva, Montserrat, Morán, Tomás, Niu, Wei, Díaz, Mònica, Aristizábal-Corrales, David, Villanueva, Alberto, Schwartz, Simó, Reinke, Valerie, Cerón, Julián
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675011/
https://ncbi.nlm.nih.gov/pubmed/23754964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003543
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