Schistosoma japonicum Soluble Egg Antigens Attenuate Invasion in a First Trimester Human Placental Trophoblast Model

BACKGROUND: Schistosomiasis affects nearly 40 million women of reproductive age, and is known to elicit a pro-inflammatory signature in the placenta. We have previously shown that antigens from schistosome eggs can elicit pro-inflammatory cytokine production from trophoblast cells specifically; howe...

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Hauptverfasser: McDonald, Emily A., Friedman, Jennifer F., Sharma, Surendra, Acosta, Luz, Pond-Tor, Sunthorn, Cheng, Ling, White, Eric S., Kurtis, Jonathan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675010/
https://ncbi.nlm.nih.gov/pubmed/23755313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002253
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