The role of citrate and phosphate anions in the mechanism of iron(III) sequestration by ferric binding protein: Kinetic studies of holoprotein formation of wild type and engineered mutants of FbpA

Ferric binding protein A (FbpA) plays a central role in the iron acquisition processes of pathogenic Neisseria gonorrhoeae, Neisseria meningitidis, and Haemophilus influenza. FbpA functions as an iron shuttle within the periplasmic space of these Gram-negative human pathogens. Iron is picked up by F...

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Hauptverfasser: Weaver, Katherine D., Gabričević, Mario, Anderson, Damon S., Adhikari, Pratima, Mietzner, Timothy A., Crumbliss, Alvin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674840/
https://ncbi.nlm.nih.gov/pubmed/20496864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902231c
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