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Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

The pubertal height growth spurt is a distinctive feature of childhood growth reflecting both the central onset of puberty and local growth factors. Although little is known about the underlying genetics, growth variability during puberty correlates with adult risks for hormone-dependent cancer and...

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Detalhes bibliográficos
Main Authors: Cousminer, Diana L., Berry, Diane J., Timpson, Nicholas J., Ang, Wei, Thiering, Elisabeth, Byrne, Enda M., Taal, H. Rob, Huikari, Ville, Bradfield, Jonathan P., Kerkhof, Marjan, Groen-Blokhuis, Maria M., Kreiner-Møller, Eskil, Marinelli, Marcella, Holst, Claus, Leinonen, Jaakko T., Perry, John R.B., Surakka, Ida, Pietiläinen, Olli, Kettunen, Johannes, Anttila, Verneri, Kaakinen, Marika, Sovio, Ulla, Pouta, Anneli, Das, Shikta, Lagou, Vasiliki, Power, Chris, Prokopenko, Inga, Evans, David M., Kemp, John P., St Pourcain, Beate, Ring, Susan, Palotie, Aarno, Kajantie, Eero, Osmond, Clive, Lehtimäki, Terho, Viikari, Jorma S., Kähönen, Mika, Warrington, Nicole M., Lye, Stephen J., Palmer, Lyle J., Tiesler, Carla M.T., Flexeder, Claudia, Montgomery, Grant W., Medland, Sarah E., Hofman, Albert, Hakonarson, Hakon, Guxens, Mònica, Bartels, Meike, Salomaa, Veikko, Murabito, Joanne M., Kaprio, Jaakko, Sørensen, Thorkild I.A., Ballester, Ferran, Bisgaard, Hans, Boomsma, Dorret I., Koppelman, Gerard H., Grant, Struan F.A., Jaddoe, Vincent W.V., Martin, Nicholas G., Heinrich, Joachim, Pennell, Craig E., Raitakari, Olli T., Eriksson, Johan G., Smith, George Davey, Hyppönen, Elina, Järvelin, Marjo-Riitta, McCarthy, Mark I., Ripatti, Samuli, Widén, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674797/
https://ncbi.nlm.nih.gov/pubmed/23449627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt104
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