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Thermodynamics of T cell receptor – peptide/MHC interactions: progress and opportunities
αβ T cell receptors (TCR) recognize peptide antigens presented by class I or class II major histocompatibility complex molecules (pMHC). Here we review the use of thermodynamic measurements in the study of TCR-pMHC interactions, with attention to the diversity in binding thermodynamics and how this...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2008
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674762/ https://ncbi.nlm.nih.gov/pubmed/18496839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.896 |
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