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Thermodynamics of T cell receptor – peptide/MHC interactions: progress and opportunities

αβ T cell receptors (TCR) recognize peptide antigens presented by class I or class II major histocompatibility complex molecules (pMHC). Here we review the use of thermodynamic measurements in the study of TCR-pMHC interactions, with attention to the diversity in binding thermodynamics and how this...

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Bibliographic Details
Main Authors: Armstrong, Kathryn M., Insaidoo, Francis K., Baker, Brian M.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674762/
https://ncbi.nlm.nih.gov/pubmed/18496839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.896
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