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A General and Efficient Approach for NMR Studies of Peptide Dynamics in Class I MHC Peptide Binding Grooves

T cell receptor recognition of peptides bound by major histocompatibility complex (MHC) proteins initiates a cellular immune response. Dynamics of peptides within MHC binding grooves can influence TCR recognition, yet NMR studies which could address this rigorously have been hindered by the expense...

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Detalhes bibliográficos
Main Authors: Insaidoo, Francis K., Zajicek, Jaroslav, Baker, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762276/
https://ncbi.nlm.nih.gov/pubmed/19772349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9008787
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