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IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells

The emergence of the adaptive immune system took a toll in the form of pathologies mediated by self-reactive cells. Regulatory T cells (T reg cells) exert a critical brake on responses of T and B lymphocytes to self- and foreign antigens. Here, we asked whether T reg cells are required to restrain N...

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Detalhes bibliográficos
Main Authors: Gasteiger, Georg, Hemmers, Saskia, Firth, Matthew A., Le Floc’h, Audrey, Huse, Morgan, Sun, Joseph C., Rudensky, Alexander Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674692/
https://ncbi.nlm.nih.gov/pubmed/23650441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122462
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