Identifying network motifs that buffer front-to-back signaling in polarized neutrophils

Neutrophil polarity relies on local, mutual inhibition to segregate incompatible signaling circuits to the leading and trailing edges. Mutual inhibition alone should lead to cells having strong fronts and weak backs or vice versa. However, analysis of cell-to-cell variation in human neutrophils reve...

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Bibliografiske detaljer
Main Authors: Wang, Yanqin, Ku, Chin-Jen, Zhang, Elizabeth R., Artyukhin, Alexander B., Weiner, Orion D., Wu, Lani F., Altschuler, Steven J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674638/
https://ncbi.nlm.nih.gov/pubmed/23665220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.009
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