Identification of HLA-A24 restricted CD8(+) Cytotoxic T-Cell Epitopes Derived from Mammaglobin-A, A Human Breast Cancer Associated Antigen

Human breast cancer associated antigen, Mammaglobin-A (Mam-A), potentially offers a novel therapeutic target as breast cancer vaccines. In this study, we define the CD8(+) CTL response to Mam-A derived candidate epitopes presented in the context of HLA-A24 (A*2402). HLA-A24 has a frequency of 72% in...

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Hlavní autoři: Tiriveedhi, Venkataswarup, Sarma, Nayan J, Subramanian, Vijay, Fleming, Timothy P., Gillanders, William E., Mohanakumar, T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674634/
https://ncbi.nlm.nih.gov/pubmed/22074997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2011.10.017
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