Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis

INTRODUCTION: The goal of this study is to investigate whether the -308G > A promoter polymorphism in the tumor necrosis factor alpha (TNFA) gene is associated with disease severity and radiologic joint damage in a large cohort of patients with rheumatoid arthritis (RA). METHODS: A long-term obse...

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Detalhes bibliográficos
Main Authors: Toonen, Erik JM, Barrera, Pilar, Fransen, Jaap, de Brouwer, Arjan PM, Eijsbouts, Agnes M, Miossec, Pierre, Marotte, Hubert, Scheffer, Hans, van Riel, Piet LCM, Franke, Barbara, Coenen, Marieke JH
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674610/
https://ncbi.nlm.nih.gov/pubmed/23217265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4110
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