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Individual Differences in Amygdala-Medial Prefrontal Anatomy Link Negative Affect, Impaired Social Functioning, and Polygenic Depression Risk

Individual differences in affective and social processes may arise from variability in amygdala-medial prefrontal (mPFC) circuitry and related genetic heterogeneity. To explore this possibility in humans, we examined the structural correlates of trait negative affect in a sample of 1050 healthy youn...

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Detalhes bibliográficos
Main Authors: Holmes, Avram J., Lee, Phil H., Hollinshead, Marisa O., Bakst, Leah, Roffman, Joshua L., Smoller, Jordan W., Buckner, Randy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674506/
https://ncbi.nlm.nih.gov/pubmed/23238724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2531-12.2012
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