Disulfide reduction abolishes tissue factor cofactor function

BACKGROUND: Tissue factor (TF), an in vivo initiator of blood coagulation, is a transmembrane protein and has two disulfides in the extracellular domain. The integrity of one cysteine pair, Cys186–Cys209, has been hypothesized to be essential for an allosteric “decryption” phenomenon, presumably reg...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Krudysz-Amblo, Jolanta, Jennings, Mark E., Knight, Tyler, Matthews, Dwight E., Mann, Kenneth G., Butenas, Saulius
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674504/
https://ncbi.nlm.nih.gov/pubmed/23434438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.02.013
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker