The prognostic impact of FLT3-ITD and NPM1 mutations in patients with relapsed acute myeloid leukemia and intermediate-risk cytogenetics

Internal tandem duplication of the fms-like tyrosine kinase-3 gene (FLT3-ITD) and nucleophosmin-1 (NPM1) mutations have prognostic importance in acute myeloid leukemia (AML) patients with intermediate-risk karyotype at diagnosis, but less is known about their utility to predict outcomes at relapse....

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Bibliografische gegevens
Hoofdauteurs: How, J, Sykes, J, Minden, M D, Gupta, V, Yee, K W L, Schimmer, A D, Schuh, A C, Kamel-Reid, S, Brandwein, J M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674456/
https://ncbi.nlm.nih.gov/pubmed/23708641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2013.14
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