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Inhibition of Janus activated kinase-3 protects against myocardial ischemia and reperfusion injury in mice

Recent studies have documented that Janus-activated kinase (JAK)–signal transducer and activator of transcription (STAT) pathway can modulate the apoptotic program in a myocardial ischemia/reperfusion (I/R) model. To date, however, limited studies have examined the role of JAK3 on myocardial I/R inj...

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Detalhes bibliográficos
Main Authors: Oh, Young-Bin, Ahn, Min, Lee, Sang-Myeong, Koh, Hyoung-Won, Lee, Sun-Hwa, Kim, Suhn Hee, Park, Byung-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674406/
https://ncbi.nlm.nih.gov/pubmed/23680658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.43
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