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NLRP3 activation induces ASC-dependent programmed necrotic cell death, which leads to neutrophilic inflammation
NLR family pyrin domain containing 3 (NLRP3) is a cytoplasmic pattern recognition receptor that regulates innate immune responses by forming a protein complex, the inflammasome. It leads to production of proinflammatory cytokine productions such as interleukin 1β (IL-1β). We and others demonstrated...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674376/ https://ncbi.nlm.nih.gov/pubmed/23703389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.169 |
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