Exenatide promotes cognitive enhancement and positive brain metabolic changes in PS1-KI mice but has no effects in 3xTg-AD animals

Recent studies have shown that type 2 diabetes mellitus (T2DM) is a risk factor for cognitive dysfunction or dementia. Insulin resistance is often associated with T2DM and can induce defective insulin signaling in the central nervous system as well as increase the risk of cognitive impairment in the...

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Main Authors: Bomba, M, Ciavardelli, D, Silvestri, E, Canzoniero, L MT, Lattanzio, R, Chiappini, P, Piantelli, M, Di Ilio, C, Consoli, A, Sensi, S L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674348/
https://ncbi.nlm.nih.gov/pubmed/23640454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.139
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