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Pre-mRNA processing factors meet the DNA damage response

It is well-known that DNA-damaging agents induce genome instability, but only recently have we begun to appreciate that chromosomes are fragile per se and frequently subject to DNA breakage. DNA replication further magnifies such fragility, because it leads to accumulation of single-stranded DNA. Re...

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Bibliografiske detaljer
Main Authors: Montecucco, Alessandra, Biamonti, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674313/
https://ncbi.nlm.nih.gov/pubmed/23761808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00102
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