Simultaneously expressed miR-424 and miR-381 synergistically suppress the proliferation and survival of renal cancer cells---Cdc2 activity is up-regulated by targeting WEE1

OBJECTIVES: MiRNAs are intrinsic RNAs that interfere with protein translation. Few studies on the synergistic effects of miRNAs have been reported. Both miR-424 and miR-381 have been individually reported to be involved in carcinogenesis. They share a common putative target, WEE1, which is described...

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Detalhes bibliográficos
Main Authors: Chen, Binghai, Duan, Lujing, Yin, Guangming, Tan, Jing, Jiang, Xianzhen
Formato: Artigo
Idioma:Inglês
Publicado em: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2013
Assuntos:
Clinical Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674285/
https://ncbi.nlm.nih.gov/pubmed/23778472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2013(06)17
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