PET Imaging of Neuropathology in Tauopathies: Progressive Supranuclear Palsy

OBJECTIVE: Currently [F-18]FDDNP is the only PET imaging probe with the ability to visualize hyperphosphorylated tau fibrillar aggregates in living subjects. In this work, we evaluate in vivo [F-18]FDDNP labeling of brain neuropathology, primarily tau fibrillar aggregates, in patients with progressi...

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Hauptverfasser: Kepe, Vladimir, Bordelon, Yvette, Boxer, Adam, Huang, Sung-Cheng, Liu, Jie, Thiede, Frederick C., Mazziotta, John C., Mendez, Mario F., Donoghue, Natacha, Small, Gary W., Barrio, Jorge R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674205/
https://ncbi.nlm.nih.gov/pubmed/23579330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-130032
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