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Attenuating myocardial ischemia by targeting A2B adenosine receptors

Due to an imbalance in oxygen supply and demand, myocardial ischemia is associated with profound tissue hypoxia. Studies of hypoxia-elicited adaptive responses during myocardial ischemia revealed a cardioprotective role for the signaling molecule adenosine. In ischemic human hearts, the A2B adenosin...

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Bibliographic Details
Main Authors: Eltzschig, Holger K., Bonney, Stephanie K., Eckle, Tobias
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674126/
https://ncbi.nlm.nih.gov/pubmed/23540714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2013.02.005
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