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Frailty in Old Age Is Associated with Decreased Interleukin-12/23 Production in Response to Toll-Like Receptor Ligation

Aging is associated with progressive alterations of immune functions, leading to higher susceptibility to bacterial and viral infections and reduced vaccine responses. Data concerning cytokine production in response to Toll-like receptor (TLR) ligands are highly variable in old people, reflecting th...

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Detalhes bibliográficos
Main Authors: Compté, Nathalie, Zouaoui Boudjeltia, Karim, Vanhaeverbeek, Michel, De Breucker, Sandra, Tassignon, Joel, Trelcat, Anne, Pepersack, Thierry, Goriely, Stanislas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673922/
https://ncbi.nlm.nih.gov/pubmed/23755218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065325
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