X-ray irradiation promotes apoptosis of hippocampal neurons through up-regulation of Cdk5 and p25

BACKGROUND: Cranial radiation therapy has been used for the treatment of primary and metastatic brain tumors. A prominent feature of brain injury induced by the radiation therapy is hippocampal dysfunction, characterized by a decline in memory. Cdk5 plays an important role in memory formation. Abnor...

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Detalhes bibliográficos
Main Authors: Sun, Ai-Min, Li, Chuan-Gang, Han, Yong-Qing, Liu, Que-Ling, Xia, Qiong, Yuan, Ya-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673899/
https://ncbi.nlm.nih.gov/pubmed/23688022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-47
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