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Production of hepatocyte like cells from human pluripotent stem cells

Large scale production of hepatocytes from a variety of genetic backgrounds would be beneficial for drug screening and to provide a source of cells to be used as a substitute for liver transplantation. However, fully functional primary hepatocytes remain difficult to expand in vitro and circumventin...

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Bibliographic Details
Main Authors: Hannan, Nicholas R.F, Segeritz, Charis-Patricia, Touboul, Thomas, Vallier, Ludovic
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673228/
https://ncbi.nlm.nih.gov/pubmed/23424751
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