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A powerful and efficient set test for genetic markers that handles confounders
Motivation: Approaches for testing sets of variants, such as a set of rare or common variants within a gene or pathway, for association with complex traits are important. In particular, set tests allow for aggregation of weak signal within a set, can capture interplay among variants and reduce the b...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673214/ https://ncbi.nlm.nih.gov/pubmed/23599503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt177 |
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