Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments

Platelet-derived growth factor receptor (PDGFR) α and β have been suggested as potential targets for treatment of rhabdomyosarcoma, the most common soft tissue sarcoma in children. This study identifies biological activities linked to PDGF signaling in rhabdomyosarcoma models and human sample collec...

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Hauptverfasser: Ehnman, Monika, Missiaglia, Edoardo, Folestad, Erika, Selfe, Joanna, Strell, Carina, Thway, Khin, Brodin, Bertha, Pietras, Kristian, Shipley, Janet, Östman, Arne, Eriksson, Ulf
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672973/
https://ncbi.nlm.nih.gov/pubmed/23338608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1646
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