A C. elegans Screening Platform for the Rapid Assessment of Chemical Disruption of Germline Function

Background: Despite the developmental impact of chromosome segregation errors, we lack the tools to assess environmental effects on the integrity of the germline in animals. Objectives: We developed an assay in Caenorhabditis elegans that fluorescently marks aneuploid embryos after chemical exposure...

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Bibliographic Details
Main Authors: Allard, Patrick, Kleinstreuer, Nicole C., Knudsen, Thomas B., Colaiácovo, Monica P.
Format: Artigo
Language:Inglês
Published: National Institute of Environmental Health Sciences 2013
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672921/
https://ncbi.nlm.nih.gov/pubmed/23603051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1206301
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