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Construction of a cDNA to the hamster CAD gene and its application toward defining the domain for aspartate transcarbamylase.

cDNA complementary to hamster mRNA encoding the CAD protein, a multifunctional protein which carries the first three enzymes of pyrimidine biosynthesis, was constructed. The longest of these recombinants (pCAD142) covers 82% of the 7.9-kilobase mRNA. Portions of the cDNA were excised and replaced by...

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Bibliographic Details
Main Authors: Shigesada, K, Stark, G R, Maley, J A, Niswander, L A, Davidson, J N
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC367292/
https://ncbi.nlm.nih.gov/pubmed/2862577
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