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Mitochondrial Free Ca(2+) Levels and Their Effects on Energy Metabolism in Drosophila Motor Nerve Terminals

Mitochondrial Ca(2+) uptake exerts dual effects on mitochondria. Ca(2+) accumulation in the mitochondrial matrix dissipates membrane potential ((Δ)Ψ(m)), but Ca(2+) binding of the intramitochondrial enzymes accelerates oxidative phosphorylation, leading to mitochondrial hyperpolarization. The levels...

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Bibliografske podrobnosti
Main Authors: Ivannikov, Maxim V., Macleod, Gregory T.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672877/
https://ncbi.nlm.nih.gov/pubmed/23746507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.03.064
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