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Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis

INTRODUCTION: Anterior cruciate ligament (ACL) degeneration is observed in most osteoarthritis (OA)-affected knee joints. However, the specific spatial and temporal relations of these changes and their association with extracellular matrix (ECM) degeneration are not well understood. The objective of...

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Bibliografiske detaljer
Main Authors: Hasegawa, Akihiko, Nakahara, Hiroyuki, Kinoshita, Mitsuo, Asahara, Hiroshi, Koziol, James, Lotz, Martin K
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672799/
https://ncbi.nlm.nih.gov/pubmed/23406989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4165
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