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The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarker

Initially discovered as an estrogen-responsive gene in breast cancer cell lines, anterior gradient 2 (AGR2) is a developmentally regulated gene belonging to the protein disulfide isomerase (PDI) gene family. Developmentally, AGR2 is expressed in the mammary gland in an estrogen-dependent manner, and...

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Bibliographic Details
Main Authors: Salmans, Michael L, Zhao, Fang, Andersen, Bogi
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672732/
https://ncbi.nlm.nih.gov/pubmed/23635006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3408
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