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The role of the circadian clock in rheumatoid arthritis

Rheumatoid arthritis exhibits diurnal variation in symptoms, with patients suffering with increased painful joint stiffness in the early morning. This correlates with an early morning rise in circulating levels of pro-inflammatory cytokines, such as interleukin-6. This temporal variation in disease...

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Detalhes bibliográficos
Main Authors: Gibbs, Julie E, Ray, David W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672712/
https://ncbi.nlm.nih.gov/pubmed/23427807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4146
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