Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer

INTRODUCTION: The phosphatidylinositol 3-kinase (PI3K) pathway is frequently activated in cancer cells through numerous mutations and epigenetic changes. The recent development of inhibitors targeting different components of the PI3K pathway may represent a valuable treatment alternative. However, p...

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Main Authors: Moestue, Siver A, Dam, Cornelia G, Gorad, Saurabh S, Kristian, Alexandr, Bofin, Anna, Mælandsmo, Gunhild M, Engebråten, Olav, Gribbestad, Ingrid S, Bjørkøy, Geir
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672699/
https://ncbi.nlm.nih.gov/pubmed/23448424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3391
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