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CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice

INTRODUCTION: The ability to ameliorate murine lupus renders regulatory T cells (Treg) a promising tool for the treatment of systemic lupus erythematosus (SLE). In consideration to the clinical translation of a Treg-based immunotherapy of SLE, we explored the potential of CD4+Foxp3+ Treg to maintain...

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Autori principali: Weigert, Olivia, von Spee, Caroline, Undeutsch, Reinmar, Kloke, Lutz, Humrich, Jens Y, Riemekasten, Gabriela
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672693/
https://ncbi.nlm.nih.gov/pubmed/23446139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4188
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