Evaluation of the novel folate receptor ligand [(18)F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis

INTRODUCTION: Detection of (subclinical) synovitis is relevant for both early diagnosis and monitoring of therapy of rheumatoid arthritis (RA). Previously, the potential of imaging (sub)clinical arthritis was demonstrated by targeting the translocator protein in activated macrophages using (R)-[(11)...

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Hauptverfasser: Gent, Yoony YJ, Weijers, Karin, Molthoff, Carla FM, Windhorst, Albert D, Huisman, Marc C, Smith, Desirée EC, Kularatne, Sumith A, Jansen, Gerrit, Low, Philip S, Lammertsma, Adriaan A, van der Laken, Conny J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672671/
https://ncbi.nlm.nih.gov/pubmed/23452511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4191
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