Transcriptional activation of the mouse Mx gene by type I interferon.

Mouse cells of the Mx+ genotype accumulate Mx mRNA in response to type I interferon (IFN). Nuclear runoff experiments show that IFN stringently regulates Mx gene expression at the level of transcription. Mx mRNA synthesis peaks about 3 h after IFN treatment, and within 5 h, Mx mRNA concentration ris...

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Main Authors: Staeheli, P, Danielson, P, Haller, O, Sutcliffe, J G
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC367267/
https://ncbi.nlm.nih.gov/pubmed/3796617
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