A carregar...
A de novo MYOC mutation detected in juvenile open angle glaucoma causes non-secretion of associated with reduced myocilin protein in aqueous humor
MYOC mutations were originally identified in patients with juvenile open angle glaucoma (JOAG). Cell culture and mouse studies suggest that MYOC mutations cause glaucoma through a dominant-negative effect on myocilin protein secretion. We tested this hypothesis with patient samples in this study. Gl...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672363/ https://ncbi.nlm.nih.gov/pubmed/23517641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmg.2013.03.002 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|