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Three Sgp Loci Act Independently as well as Synergistically to Elevate the Expression of Specific Endogenous Retroviruses Implicated in Murine Lupus
Endogenous retroviruses are implicated in murine lupus nephritis. They provide a source of nephritogenic retroviral gp70-anti-gp70 immune complexes through the production of serum gp70 protein and anti-gp70 autoantibodies as a result of the activation of TLR7. The Sgp (serum gp70 production) loci id...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672360/ https://ncbi.nlm.nih.gov/pubmed/23465716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.01.014 |
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