In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae

OBJECTIVES: Alterations in the mechanical loading environment in joints may have both beneficial and detrimental effects on articular cartilage and subchondral bone and subsequently influence the development of osteoarthritis (OA). We used an in vivo tibial loading model to investigate the adaptive...

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Main Authors: Ko, Frank C., Dragomir, Cecilia, Plumb, Darren A., Goldring, Steven R., Wright, Timothy M., Goldring, Mary B., van der Meulen, Marjolein C.H.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672344/
https://ncbi.nlm.nih.gov/pubmed/23436303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37906
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