High-mobility group box 1 protein (HMGB1) neutralization ameliorates experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is an autoimmune, demyelinating disease and as such, the gold standard of treatment is to selectively suppress the pathogenic autoimmune response without compromising the entire arm of the adaptive immune response. One target of this strategy lying upstream of the pathologic...

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Main Authors: Robinson, Andrew P., Caldis, Matthew W., Harp, Christopher T., Goings, Gwendolyn E., Miller, Stephen D.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672339/
https://ncbi.nlm.nih.gov/pubmed/23514872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.02.005
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