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DOPAMINE D2 RECEPTOR ACTIVATION LEADS TO AN UPREGULATION OF GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR VIA Gβγ-ERK1/2-DEPENDENT INDUCTION OF ZIF268
Glial cell line-derived neurotrophic factor (GDNF) is a potent growth factor essential to the development, survival, and function of dopaminergic neurons (Airaksinen and Saarma, 2002). The molecular mechanisms underlying GDNF expression remain elusive, thus, we set out to identify a signaling pathwa...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672320/ https://ncbi.nlm.nih.gov/pubmed/23373701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12178 |
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