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The archaeal DnaG protein needs Csl4 for binding to the exosome and enhances its interaction with adenine-rich RNAs

The archaeal RNA-degrading exosome contains a catalytically active hexameric core, an RNA-binding cap formed by Rrp4 and Csl4 and the protein annotated as DnaG (bacterial type primase) with so-far-unknown functions in RNA metabolism. We found that the archaeal DnaG binds to the Csl4-exosome but not...

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Auteurs principaux: Hou, Linlin, Klug, Gabriele, Evguenieva-Hackenberg, Elena
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672285/
https://ncbi.nlm.nih.gov/pubmed/23324612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23450
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