Protein kinase B/Akt is required for complete Freund’s adjuvant-induced upregulation of Nav1.7 and Nav1.8 in primary sensory neurons

Voltage-gated sodium channels (Nav) are essential for the generation and conduction of action potentials. Peripheral inflammation increases the expression of Nav1.7 and Nav1.8 in dorsal root ganglion (DRG) neurons, suggesting that they participate in the induction and maintenance of chronic inflamma...

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Bibliographic Details
Main Authors: Liang, Lingli, Fan, Longchang, Tao, Bo, Yaster, Myron, Tao, Yuan-Xiang
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672264/
https://ncbi.nlm.nih.gov/pubmed/23642408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2013.01.778
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