Application of Hyperbranched Rolling Circle Amplification for Direct Detection of Mycobacterium Tuberculosis in Clinical Sputum Specimens

BACKGROUND: Global tuberculosis (TB) control is encumbered by the lack of a rapid and simple detection method for diagnosis, especially in low-resource areas. An isothermal amplification method, hyperbranched rolling circle amplification (HRCA), was optimized to detect Mycobacterium tuberculosis (Mt...

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Autors principals: Liu, Yang, Guo, Yan-Ling, Jiang, Guang-Lu, Zhou, Shi-Jie, Sun, Qi, Chen, Xi, Chang, Xiu-Jun, Xing, Ai-Ying, Du, Feng-Jiao, Jia, Hong-Yan, Zhang, Zong-De
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672175/
https://ncbi.nlm.nih.gov/pubmed/23750210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064583
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