Epigenetic therapy in allogeneic hematopoietic stem cell transplantation

DNA methylation and other epigenetic phenomena appear to be relevant in the pathogenesis of several malignant disorders. DNA methyltransferases add methyl groups to cytosine-phosphate-guanine (CpG) islandsleading to gene promoter silencing. The DNA methyltransferases inhibitors azacitidine and decit...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Bashir, Qaiser, William, Basem Magdy, Garcia-Manero, Guillermo, de Lima, Marcos
Materialtyp: Artigo
Språk:Inglês
Publicerad: Associação Brasileira de Hematologia e Hemoterapia 2013
Ämnen:
Review Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672123/
https://ncbi.nlm.nih.gov/pubmed/23741191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20130034
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